Slime Gun Guide: How to Unlock & Maximize DPS
Everything about the Slime Gun in Slime RNG. Unlock requirements, targeting mechanics, best slime pairings, and DPS optimization strategies.
Everything about the Slime Gun in Slime RNG. Unlock requirements, targeting mechanics, best slime pairings, and DPS optimization strategies.
Contents
The Slime Gun is a player-controlled weapon introduced in the May 2026 update that lets you actively participate in combat instead of relying entirely on AFK auto-battle. By marking enemies, you direct your slimes to focus fire on specific targets — dramatically increasing kill speed and Goop farming efficiency.
What Is the Slime Gun?
The Slime Gun is the first active combat mechanic in Slime RNG. Previously, all combat was passive — your equipped slimes would auto-attack nearby enemies. The Slime Gun changes this by letting you mark specific enemies, causing all your slimes to prioritize that target. This is especially powerful in high-zone farming where enemy HP is high and focused DPS matters.
Slime Gun mechanics verified via AllThings.how coverage of the May 2026 update and Game8 beginner guides. Exact damage multiplier values are approximate and may be refined as community testing continues.
How to Unlock
- 1Open the Upgrades MenuClick the Upgrades button in your game interface to open the upgrade tree.
- 2Navigate to the Player TabSwitch to the Player section of the Upgrades menu. The Slime Gun upgrade is located here, separate from the roll and enemy upgrade paths.
- 3Purchase the Slime Gun UpgradeBuy the Slime Gun node. Once purchased, the gun becomes permanently available in your loadout.
- 4Equip and UseThe Slime Gun appears as a new control. Click on enemies to mark them — your slimes will immediately focus fire on marked targets.
Targeting Mechanics
The Slime Gun uses an auto-lock targeting system. When you click on or near an enemy, the gun locks onto that target and marks it. All your equipped slimes will then prioritize attacking the marked enemy until it is defeated or you mark a new target.
Best Slime Pairings
The Slime Gun benefits most from slimes with high single-target damage. Since all slimes focus on one enemy, you want raw DPS over area-of-effect abilities.
| Slime Type | Why It Works | Synergy Rating | Source |
|---|---|---|---|
| High-Damage Exotic Slimes | Maximum single-target burst when focused | ★★★★★ | Community testing |
| Crafted Slimes (Thorn, Geode) | Strong base stats + crafting bonuses stack with focus fire | ★★★★ | In-game + Fandom Wiki |
| Inverted Variants | Highest raw stats in the game, devastating when focused | ★★★★★ | In-game |
| Speed-Boosted Slimes | Fast attack speed means more hits per second on marked target | ★★★★ | Community testing |
Pair the Slime Gun with Power Fruits that boost single-target damage (Lightning, Fire). The focused fire from marking + damage multiplier from Power Fruits creates a massive DPS spike on the marked enemy.
DPS Optimization Strategy
FAQ
No. The Slime Gun requires active clicking to mark targets. When you are not actively using it, your slimes attack normally. It is a tool for active play sessions, not AFK farming.
Yes. Once unlocked, the Slime Gun works in every zone. However, it provides the most value in high-level zones (20+) where enemies have enough HP that focused fire significantly outperforms spread auto-attacks.
The Slime Gun primarily functions as a targeting tool — it marks enemies for your slimes to focus. The gun itself may deal minor damage on hit, but the real value is the team-wide focus fire it enables.